Resumo
Objetivo: Analisar as consequências metabólicas associadas ao uso de antipsicóticos em pacientes com obesidade, com ênfase nas alterações como ganho de peso, resistência à insulina, dislipidemias e risco de desenvolvimento de síndrome metabólica, considerando os diferentes perfis de antipsicóticos e suas implicações na saúde metabólica desses indivíduos. Métodos: Trata-se de uma revisão integrativa da literatura, com artigos de 2020 a 2025, nos idiomas português e inglês e com texto completo disponível. A questão norteadora foi: Quais são as consequências metabólicas associadas ao uso de antipsicóticos em pacientes com obesidade?. A pesquisa foi realizada em junho de 2025, nas bases de dados: Biblioteca Virtual em Saúde (BVS), Serviços da National Library of Medicine (PUBMED) e Caribe em Ciências de Saúde (LILACS), utilizando os Descritores em Ciências da Saúde (DeCS) em inglês: Antipsychotic Agents, Obesity, Body Weight,Insulin Resistance e Metabolic Syndrome, combinados com operador booleano “AND”. Resultados: Foram analisados nove artigos que atenderam aos critérios de inclusão e exclusão, evidenciando principais consequências metabólicas: o ganho de peso, a resistência à insulina e o risco de síndrome metabólica. Considerações finais: O estudo reforça a importância do monitoramento contínuo e de estratégias terapêuticas integradas. A heterogeneidade dos estudos se apresenta como limitação à generalização dos resultados.
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