Google Scholar | Citations: 16429| h-index: 32 | i10-index: 482
Challenges of puerperal infections: epidemiology, risk factors, and management
PDF (Portuguese (Brazil))

Keywords

Puerperal women
Puerperal infections
Prevention
Clinical practices

How to Cite

Challenges of puerperal infections: epidemiology, risk factors, and management. (2025). Electronic Journal Collection Health, 25, e19031. https://doi.org/10.25248/reas.e19031.2025

Copyright © | All rights reserved.

The journal holds the exclusive copyright for the publication of this article under the terms of Brazilian law 9610/98.

Partial reproduction
The use of parts of the texts, figures and questionnaire of the article is free, being mandatory the citation of the authors and journal.

Total reproduction
It is expressly prohibited and must be authorized by the journal.

Abstract

Objective: To identify and analyze the most effective strategies for preventing puerperal infections based on current practices and recommendations to reduce their postpartum incidence. Methods: This is an integrative literature review using the PubMed Central (PMC) database. The search strategy involved the term: (("prevent" OR "prevention and control") AND ("puerperal infection"[MeSH Terms] OR ("puerperal")). The initial search resulted in 1,422 articles, of which 16 were selected after applying inclusion and exclusion criteria. Results: Adequate antimicrobial prophylaxis, especially before cesarean sections, strict hygiene practices, and awareness of postnatal care among pregnant women are the main prevention strategies. The review also highlighted factors associated with an increased risk of puerperal infections, including limited knowledge of preventive practices, lack of access to medical care, variations in antibiotic prophylaxis practices, unplanned cesarean sections, prolonged labor or multiple vaginal exams, iron-deficiency anemia, gestational diabetes, maternal obesity, advanced maternal age, in vitro fertilization, inadequate prenatal care, and low birth weight. Final considerations: The implementation of standardized antimicrobial prophylaxis protocols and educational programs for healthcare professionals and pregnant women is necessary, along with an integrated approach to reduce high rates of puerperal infections.

PDF (Portuguese (Brazil))

References

AINEBYONA H, et. al. Prevalence of Maternal Fever and Associated Factors among Postnatal Women at Kawempe National Referral Hospital, Uganda: A Preliminary Study. International journal of environmental research and public health, 2024; 21(3): 316.

BAKHTAWAR S, et. al. Risk factors for postpartum sepsis: a nested case-control study. BMC pregnancy and childbirth, 2020; 20(297): 1-7.

BISHAW KA, et al. Prevention of puerperal sepsis in northwest Ethiopia: Knowledge and practice of postnatal women; A multicenter cross-sectional study. SAGE Open Medicine, 2022; 10: 20503121221085842.

BOUSHRA M, RAHMAN O. Postpartum Infection. StatPearls. 2024; 1-14.

HAMDY MA, et al. Postpartum endometritis after uterine cleaning versus no cleaning in cesarean sections: Randomized clinical trial. Journal of Obstetrics and Gynaecology Research, 2021; 47(4): 1330-1336.

HILBERT M. Antiseptics leave the Clinic- The introduction of (Puerperal) Prophlaxis in Austrian Midwifery Education (1870s-1880s). Social History of Medicine, 2022; 35(1): 97-120.

IGWEMADU GT, et al. Single-dose versus multiple-dose antibiotics prophylaxis for preventing caesarean section postpartum infections: A randomized controlled trial. Women's Health, 2022; 18: 1–8.

KUHR K, et al. Postoperative infections after non-elective cesarean section – a retrospective cohort study of prevalence and risk factors at a single center in Denmark administering prophylactic antibiotics after cord clamping. BMC Pregnancy and Childbirth, 2022; 22(1): 945.

KVALVIK SA, et al. Obstetric infections and clinical characteristics of maternal sepsis: a hospital based retrospective cohort study. Scientific Reports, 2024; 14(1): 6067.

LAMFEL R, et al. A randomised trial comparing preoperative administration of single-dose kefazolin to kefazolin plus metronidazole as prophylactic antibiotics at caesarean section. South African Medical Journal, 2024; 114(6): 40-44.

LI P, et al. Incidence, temporal trends and risk factors of puerperal infection in Mainland China: a meta-analysis of epidemiological studies from recent decade (2010-2020). BMC Pregnancy and Childbirth, 2023; 23 (1): 815.

LIU P, et. al. Maternal sepsis in pregnancy and the puerperal periods: a cross-sectional study. Frontiers in medicine, 2023; 10: 1126807.

MARKWEI MT, et al. Preincision adjunctive prophylaxis for cesarean deliveries a systematic review and meta-analysis. American Journal of Obstetrics and Gynecology, 2021; 225(4): 13.

NGUNYI YL, et al. Determinants and aetiologies of postpartum pyrexia; a retrospective analysis in a tertiary health facility in the Littoral Region of Cameroon. BMC Pregnancy and Childbirth, 2020; 20(167): 1-7.

NNAGBO EJ, et al. Effectiveness of Chlorhexidine vaginal cleansing in reducing post-caesarean endometritis at two tertiary hospitals in Enugu, Nigeria: A randomized controlled trial. Tropical Doctor, 2023; 53(1): 50–56.

OBEN AG, et al. A systematic review of biomarkers associated with maternal infection in pregnant and postpartum women. International Journal of Gynecology & Obstetrics, 2022; 157(1): 42–50.

SONG H, et al. Risk factors, changes in serum inflammatory factors, and clinical prevention and control measures for puerperal infection. Journal of clinical laboratory analysis, 2020; 34(3): 23047.

TEFERI SM, el al. Reported self-care practice toward prevention of puerperal sepsis and associated factors among postnatal mothers: Community-based cross-sectional study. Sage Open Medicine, 2024; 12: 1-10.

WINTHER ACR, et al. Prophylactic antibiotics in caesarean delivery before or after cord clamping-protecting the mother at the expense of the infant's microbiota? BJOG: an international journal of obstetrics and gynaecology, 2020; 127(2): 203-206.

YUAN H, et. al. Epidemiological characteristics and risk factors of obstetric infection after the Universal Two-Child Policy in North China: a 5-year retrospective study based on 268,311 cases. BMC infectious diseases, 2022; 22(1): 878.

ZHONG X, et al. Epidemiology and clinical features of maternal sepsis: A retrospective study of whole pregnancy period. Medicine, 2022; 101(40): 30599.