Abstract
Objective: Discuss the possible influence of Helicobacter pylori as a determining factor in Gastroesophageal Reflux Disease (GERD) and its possible complications. Methods: This is an Integrative Literature Review in which the NCBI, PubMed and SciELO databases were used. The descriptors chosen were “Helicobacter pylori”, “gastroesophageal reflux”, “lower esophageal sphincter”. Thus, 15 articles from 2018 to 2021 were chosen for review. Results: H. pylori infection produces changes in stomach pH and, considering that GERD causes symptoms associated with repercussions of acidic gastric contents in the esophagus, eradication therapy can, in addition to correcting the pH, improve reflux symptoms. On the other hand, this relationship may not exist or the infection may even worsen the GERD picture, depending on several genetic and environmental factors. Final considerations: Further studies on the influence of H. pylori infection on GERD should be carried out, especially in the West, due to the high prevalence of the two pathologies, so that the best management is done in patients with gastroesophageal diseases.