Abstract
Objective: The objective of this study was to address the risks, benefits, difficulties and sexual lifestyle of the most vulnerable individuals. Methodology: It was made a critical literature review and described the psychosocial needs of people socially regarded as a risk behavior between 2013 to 2018 on EBSCO containing data base: MEDLINE, Academic Search Elite, Dentistry & Oral Sciences Source and Engineering, as well the data base PlosOne, BVS e Scielo. Results: Thirteen papers selected were divided by contents, therapeutic use, approching the risks, benefits, difficulties and sexual lifestyle. Three (03) talk about Pre-Exposure Prophylaxis (PrEP) within the scope of prevention, one (01) about infection factors, one (01) regarding to Sexual Health, eight (08) in terms of PrEP. Conclusion: It is necessary more PrEP awareness through marketing campaigns, trained health professionals and capacitated, in order to counsel the PrEP candidates and users about it is effectiveness and alternative for who are living with HIV wishing to have children biologically natural.