Abstract
Objective: To develop an antiacne gel-cream based on Copaífera officinalis L oil. (copaíba) and to carry out a quality control of the same. Methods: A formulation was developed and the oil extracted from the plant was incorporated in the formulation. The compatibility between the formulation and oil was verified. The organoleptic tests (appearance, color and odor), physical-chemical (pH, density and spreadability) and microbiological tests were carried out at 0 and 30 days after production, as well as centrifugation and temperature stress tests in order to verify possible instabilities. Results: In the incorporation test, the best concentration was 3.5%, with no alterations. The centrifugation test did not show phase separation and precipitation, as well as thermal stress test, in which the product was subjected to high temperature conditions. The gel-cream exhibited a slightly green color, gel-like appearance, characteristic odor, pH , within safety standards (5.0-5.5), density 0.977420g / cm³ - 0.99820g / cm³ and good spreadability, this latter increased as the weight was increased. Although the sample showed microbial and fungicidal growth, the number of Colony Forming Units is below the maximum limit. Conclusion: Therefore, the gel-cream displays a high cosmetic profile, with no instabilities, and it is considered adequate according to the specified safety and efficacy standards.