Keywords
Stress
Gastrointestinal microbiome
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Abstract
Objective: To investigate how the gut microbiota influences the stress response in adults. Methods: This is an integrative literature review, including open-access articles published in the last five years. The PICo strategy was adopted: P: adults, I: stress, Co: gut microbiota. Based on this, the guiding question was defined: How does the gut microbiome influence stress in adults? The search was conducted in the databases: LILACS, PubMed, and Web of Science, resulting in 85 articles using Health Sciences Descriptors (DeCS): adults, stress, gastrointestinal microbiome, combined with the Boolean operator “AND”. Results: Fifteen articles met the inclusion and exclusion criteria. The findings showed the involvement of the gut microbiota in regulating the stress response through the gut-brain axis, the influence of the hypothalamic-pituitary-adrenal axis, and the beneficial effects of probiotic and prebiotic supplementation in reducing stress and systemic inflammation. Final considerations: The gut microbiota is an important modulator of the stress response in adults and represents a promising target for interventions aimed at improving quality of life in aspects such as sleep and mental health. It can be modulated through various approaches and outcomes.
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