Resumen
Objetivo: Analizar la relación entre la fisiopatología de las crisis de migraña en mujeres y las hormonas sexuales femeninas, considerando las variaciones hormonales durante las diferentes fases reproductivas. Métodos: Revisión integrativa basada en artículos en inglés publicados entre 2014 y 2024. Las búsquedas se realizaron en las bases de datos Portal Regional de la Biblioteca Virtual en Salud (PR-BVS) y National Library of Medicine (PubMed), utilizando Descriptores en Ciencias de la Salud (DeCS): "migraine", "sex hormones" y "women", combinados con el operador booleano "AND". Resultados: Se incluyeron 23 artículos tras aplicar los criterios de inclusión y exclusión. Los estudios destacan la conexión entre la fluctuación de los niveles hormonales femeninos a lo largo de la vida reproductiva y la patogénesis de la migraña. Conclusión: La mayor prevalencia de la migraña en mujeres parece estar asociada con factores neuroendocrinos y fluctuaciones hormonales que participan en la fisiopatología de las crisis dolorosas, destacando la importancia de posibles enfoques terapéuticos futuros.
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