Resumen
Objetivo: Comparar el índice de Tobin y la relación P0,1/MIP como factores predictivos del destete de la ventilación mecánica en pacientes adultos. Métodos: Revisión sistemática realizada según las guías del Cochrane Handbook, PRISMA y AMSTAR 2. Se incluyeron ensayos clínicos aleatorizados que utilizaron el Índice de Tobin y la relación P0.1/MIP como predictores de destete. Dos revisores independientes realizaron la selección de estudios, el análisis de sesgo (RoB 2) y la evaluación de la calidad de la evidencia (GRADEpro GDT). Resultados: Solo dos estudios cumplieron los criterios, totalizando 217 pacientes. Aunque el Índice de Tobin e más citado en la literatura, no se encontro diferencia significativa em la precisión predictiva los dos indicadores. Ambos estudios presentaron alto riesgo de sesgo y baja calidad de evidencia. Consideraciones finales: Tanto el Índice de Tobin como la relación P0.1/MIP son herramientas confiables para predecir el destete exitoso de la VMI, pero ninguno demostró superioridade clara. Los resultados sobre tiempo de ventilación y mortalidad no fueron explorados adecuadamente.
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