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Manifestaciones clínicas y complicaciones del Síndrome Post-COVID-19 en adultos
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Palabras clave

Complicaciones
COVID Largo
Signos y Síntomas
Síndrome Post Agudo de COVID-19

Cómo citar

Manifestaciones clínicas y complicaciones del Síndrome Post-COVID-19 en adultos. (2024). Revista Eletrônica Acervo Saúde, 24(4), e15247. https://doi.org/10.25248/reas.e15247.2024

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Resumen

Objetivo: Definir las principales manifestaciones clínicas y complicaciones del Síndrome Post-COVID-19. Métodos: Se trata de una revisión integradora realizada mediante búsquedas en las bases de datos PubMed y BVS. Luego de aplicar los criterios de elegibilidad, se seleccionaron 20 artículos. Resultados: Existe una alta prevalencia de COVID prolongado en casos leves, moderados y graves de COVID-19, estando caracterizada por secuelas multisistémicas. Se observó predominio de disnea, mialgia y fatiga como síntomas físicos característicos del COVID Largo, además de anhedonia, confusión mental, deterioro cognitivo y síntomas de estrés postraumático constituyendo las principales manifestaciones clínicas que afectan la salud mental. Entre las complicaciones predominantes se reportaron dolor torácico, enfermedades cardíacas y pulmonares, neuropatía autonómica y pérdida de memoria. Consideraciones finales: Se considera que la investigación diagnóstica basada en síntomas y el manejo adecuado de las condiciones de Síndrome Post Agudo de COVID-19 puede mejorar la calidad de vida y recuperación de los pacientes, reduciendo costos sociales, personales y del sistema de salud.

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Referencias

AYOUBKHANI D, et al. Trajectory of long covid symptoms after covid-19 vaccination: community-based cohort study BMJ, 2022; 377: e069676.

BELLEN M, et al. Long-term sequelae are highly prevalent one year after hospitalization for severe COVID-19. Nature Journal, 2021; 11: 1-10.

BOTELHO LLR, et al. O método da revisão integrativa nos estudos organizacionais. Gestão e Sociedade, 2011; 5: 121-136.

BRASIL. Secretaria de Saúde do Distrito Federal. BOLETIM EPIDEMIOLÓGICO SEMANAL N 983. Disponível em: https://www.saude.df.gov.br/documents/37101/0/SEM_Boletim_Covid_n%C2%BA+983+DF+2023.pdf. Acesso em: 11 de out. 2023.

Coronavírus Brasil. 2023. In Painel Coronavírus. Disponível em: https://covid.saude.gov.br/. Acesso em: 18 out. 2023.

DAVIS HE, et al. Long COVID: major findings, mechanisms and recommendations. Nature Reviews Microbiology, 2023; 21: 133-146.

DENIS A, et al. Multiorgan impairment in low-risk individuals with post-COVID-19 syndrome: a prospective, community-based study. BMJ Open, 2021; 11: e048391.

EVANS RA, et al. Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation [sic] in the UK: a prospective observational study. The Lancet Respiratory Medicine, 2022; 10: 761-775.

FORTINI A, et al. One‑year evolution of DLCO changes and respiratory symptoms in patients with post COVID‑19 respiratory syndrome. Infection, 2022; 50: 513-517.

FUNG KW, et al. Prevalence and characteristics of long COVID in elderly patients: An observational cohort study of over 2 million adults in the US. PLOS Medicine, 2023; 20: e1004194.

HOFFER EP, Long COVID: Does It Exist? What Is It? We Can Do We [sic] For Sufferers? American Journal of Medicine, 2021; 134: 1310-1311.

KARUNA S, et al. Post-COVID symptom profiles and duration in a global convalescent COVID-19 observational cohort: Correlations with demographics, medical history, acute COVID-19 severity and global region. Journal of Global Health, 2023; 13: 06020.

LOGUE, et al. Sequelae in Adults at 6 Months After COVID-19 Infection. JAMA network open, 2021; 4: e210830.

MOENS MA, et al. Health-related quality of life in persons post-COVID-19 infection in comparison to normative controls and chronic pain patients. Frontiers in Public Health, 2022; 10: 01-12.

NAIK S, et al. Post COVID-19 sequelae: A prospective observational study from Northern India. Drug Discoveries & Therapeutics, 2021; 15: 254-260.

O’CONNOR RJ, et al. The COVID‐19 Yorkshire Rehabilitation Scale (C19‐YRS): Application and psychometric analysis in a post‐COVID‐19 syndrome cohort. Journal of Medical Virology, 2021; 94: 1027-1034.

OMS. A clinical case definition of post COVID-19 condition by a Delphi consensus. 2021. Disponível em: https://iris.who.int/bitstream/handle/10665/345824/WHO-2019-nCoV-Post-COVID-19-condition-Clinical-case-definition-2021.1-eng.pdf?sequence=1. Acesso em: 11 de out. 2023.

SAIGAL A, et al. Cross-sectional study evaluating the impact of SARS-CoV-2 variants on Long COVID outcomes in UK hospital survivors. BMJ Open Respiratory Research, 2023, 10(1): e00166.

SAMPER-PARDO M, et al. "Clinical characterization and factors associated with quality of life in Long COVID patients: Secondary data analysis from a randomized clinical trial." Plos one, 2023: 18(5): e0278728.

SAYED S. Post-COVID-19 fatigue and anhedonia: A cross-sectional study and their correlation to post-recovery period. Neuropsychopharmacology Reports, 2020; 41: 50-55.

SEANG S, et al. Long COVID-19 symptoms: Clinical characteristics and recovery rate among non-severe outpatients over a six-month follow-up. Infectious Diseases Now, 2022; 52: 165-169.

SPATZ ES, et al. Three-Month Symptom Profiles Among Symptomatic Adults With Positive and Negative Severe Acute Respiratory Syndrome Coronavirus 2 Tests: A Prospective Cohort Study From the INSPIRE Group. Clinical Infectious Diseases, 2023; 76: 1559-1566.

STELLA AB, et al. Autonomic dysfunction in post‐COVID patients with and without neurological symptoms: a prospective multidomain observational study. Journal of Neurology, 2022; 269: 587-596.

TABACOF L, et al. Post-acute COVID-19 Syndrome Negatively Impacts Physical Function, Cognitive Function, Health-Related Quality of Life, and Participation. American Journal of Physical Medicine & Rehabilitation, 2022; 101: 48-52.

TWOMEY R, et al. Chronic Fatigue and Postexertional Malaise in People Living with Long COVID: An Observational Study. Oxford University Press, 2022; 102: 1-12.

WALKER S, et al. Impact of fatigue as the primary determinant of functional limitations among patients with post-COVID-19 syndrome: a cross-sectional observational study. BMJ Open, 2023; 13: e069217.

YONG SJ, LIU S. Proposed subtypes of post-COVID-19 syndrome (or long-COVID) and their respective potential therapies. Reviews in Medical Virology, 2022; 32: e2315.