Perfil epidemiológico e correlação entre comorbidades com o tempo de internação, desfecho e necessidade de ventilação invasiva em indivíduos com Covid-19 em um Hospital de referência do estado do Pará, Brasil
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Publicado
Aug 16, 2022
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Resumo
Objetivo: Traçar perfil epidemiológico e comparar tempo de internação, desfecho e necessidade de ventilação invasiva em pacientes com comorbidades e aqueles sem comorbidades em indivíduos internados devido a COVID-19 em um hospital de referência do estado do Pará, Brasil. Métodos: Trata-se de um estudo transversal descritivo, conduzido com a análise de 67 prontuários de indivíduos, de ambos os sexos. Foram coletados dados de sexo, faixa etária, comorbidades, tempo de internação, desfecho e uso de ventilação invasiva (VI), esses dados estratificados e correlacionados isoladamente e entre si: presença ou não de comorbidade, desfecho, tempo de internação x Hipertensão Arterial Sistêmica (HAS) x desfecho, tempo de internação x Diabetes x desfecho, VI x HAS e VI x Diabetes. Os dados obtidos foram analisados por estatística descritiva com auxílio do software Biostat 5.3. O estudo foi aprovado por Comitê de Ética em Pesquisa. Resultados: Amostra revelou que metade dos pacientes possuíam comorbidades, e, dentre todos, 58% receberam alta e 25% morreram. Enquanto aqueles com comorbidades permaneceram mais tempo internados, foram os que mais morreram e necessitaram de VI. Conclusão: Foi possível estabelecer uma correlação entre doentes crônicos e seus desfechos. Porém, ainda é precário o preenchimento correto dos prontuários, sendo inúmeros os inutilizáveis.
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Como Citar
BarrosH. M., DillonA. de O., Rosas JuniorF. I. T., SarmanhoN. B., & BritoC. V. B. (2022). Perfil epidemiológico e correlação entre comorbidades com o tempo de internação, desfecho e necessidade de ventilação invasiva em indivíduos com Covid-19 em um Hospital de referência do estado do Pará, Brasil. Revista Eletrônica Acervo Saúde, 15(8), e10825. https://doi.org/10.25248/reas.e10825.2022
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Referências
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26. USHER K, et al. Life in the pandemic: social isolation and mental health. Journal Of Clinical Nursing, 2020; 29(15-16): 2756-2757.
27. VAIRA LA, et al. Anosmia and Ageusia: common findings in covid ⠰19 patients. The Laryngoscope, 2020; 130(7): 1787-1787.
28. VAN DOREMALEN N, et al. Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1. New England Journal Of Medicine, 2020; 382(16): 1564-1567.
29. WANG D, et al. Clinical Characteristics of 138 Hospitalized Patients with 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China. JAMA, 2020; 323(11): 1061–1069.
30. WEI Y, et al. Comprehensive estimation for the length and dispersion of COVID-19 incubation period: a systematic review and meta-analysis. Infection, 2021; 1-11.
31. YUAN J, et al. The correlation between viral clearance and biochemical outcomes of 94 COVID-19 infected discharged patients. Inflammation Research, 2020; 69(6): 599-606.
32. ZHENG YY, et al. COVID-19 and the cardiovascular system. Nat Rev Cardiol., 2020; 17: 259–260.
33. DANIELSEN AC, et al. Sex disparities in COVID-19 outcomes in the United States: quantifying and contextualizing variation. Social Science & Medicine, 2022; 294: 114716.
34. TAKANASHI T, et al. Sex differences in immune responses that underlie COVID-19 disease outcomes. Nature, 2020; 588: 315–320.
2. BRASIL. Ministério da Saúde. 2022. Coronavírus Brasil. In: PAINEL GERAL: Painel Coronavírus. Disponível em: https://covid.saude.gov.br/. Acessado em: 31 de julho de 2022.
3. CALFEE CS, et al. Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomized controlled trials. The Lancet Respiratory Medicine, 2014; 2(8): 611-620.
4. DENG Y, et al. Associação da Hipertensão com a Gravidade e a Mortalidade de Pacientes Hospitalizados com COVID-19 em Wuhan, China: estudo unicêntrico e retrospectivo. Arquivos Brasileiros de Cardiologia, 2021; 5(117): 911-921.
5. DU Z, et al. Detection of antibodies against SARS‐CoV‐2 in patients with COVID‐19. Journal Of Medical Virology, 2020; 92(10): 1735-1738.
6. FADINI GP, et al. Prevalence and impact of diabetes among people infected with SARS-CoV-2. J Endocrinol Invest., 2020; 43(6): 867-869.
7. FANG X, et al. Epidemiological, comorbidity factors with severity and prognosis of COVID-19: a systematic review and meta-analysis. Aging, 2020; 12(13): 12493-12503.
8. FERNÁNDEZ-DE-LAS-PEÑAS C, et al. Prevalence of post-COVID-19 symptoms in hospitalized and non-hospitalized COVID-19 survivors: a systematic review and meta-analysis. European Journal Of Internal Medicine, 2021; 92: 55-70.
9. GERVASIO CF, et al. Estenose traqueal após traqueostomia para ventilação mecânica em pneumonia COVID-19 -relato de 2 casos do norte da Itália. O jornal americano de relatos de casos, 2020; 21.
10. GHOLAMI M, et al. COVID-19 and healthcare workers: a systematic review and meta-analysis. International Journal Of Infectious Diseases, 2021; 104: 335-346.
11. GOLD J, et al. Race, Ethnicity, and Age Trends in Persons Who Died from COVID-19 - United States, May-August 2020. MMWR Morb Mortal Wkly Rep., 2020; 69(42): 1517-1521.
12. GUO W, et al. Diabetes is a risk factor for the progression and prognosis of covid-19. Diabetes Metab Res Rev., 2020; 36(7): e3319.
13. HAN X, et al. Novel Coronavirus Pneumonia (COVID-19) Progression Course in 17 Discharged Patients: Comparison of Clinical and Thin-Section CT Features During Recovery, Clinical Infectious Diseases, 2020; 71(15): 723–731.
14. KUMAR A, et al. Is diabetes mellitus associated with mortality and severity of COVID-19? A meta-analysis. Diabetes & Metabolic Syndrome, 2020; 14(4): 535-545.
15. LI J, et al. Epidemiology of COVID‐19: a systematic review and metaanalysis of clinical characteristics, risk factors, and outcomes. Journal Of Medical Virology, Shandong, China, 2020; 93(3): 1449-1458.
16. LOHIA P, et al. Metabolic syndrome and clinical outcomes in patients infected with COVID ‐19: does age, sex, and race of the patient with metabolic syndrome matter? Journal Of Diabetes, 2021; 13(5): 420-429.
17. MAHAMAT-SALEH Y, et al. Diabetes, hypertension, body mass index, smoking and COVID-19-related mortality: a systematic review and meta-analysis of observational studies. BMJ Open, 2021; 11(10): 1-15.
18. MANDAL S, et al. ‘Long-COVID’: a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for covid-19. Thorax, 2020; 76(4): 396-398.
19. NANDY K, et al. Coronavirus disease (COVID-19): a systematic review and meta-analysis to evaluate the impact of various comorbidities on serious events. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Wuhan, China, 2020; 14(5): 1017-1025.
20. RAHIMI NR, et al. Bidirectional association between COVID-19 and the environment: a systematic review. Environmental Research, 2021; 194: 1-19.
21. RITTER WRG, RODRIGUES WF. Efeitos da ventilação mecânica não-invasiva com duas pressões no tratamento de adultos com Covid-19 que evoluíram com enfisema subcutâneo: uma revisão narrativa. Revista Eletrônica Acervo Saúde, 2022; 15(5): e10177.
22. SANTURA I, et al. Chest computed tomography versus RT-PCR in early diagnostics of COVID-19 – a systematic review with meta-analysis. Polish Journal Of Radiology, Department Of Nutrition And Drug Research, Institute Of Public Health, Faculty Of Health Sciences, Jagiellonian University Medical College, 2021; 86(1): 518-531.
23. SATHISH T, et al. Proportion of newly diagnosed diabetes in COVID ‐19 patients: a systematic review and metaanalysis. Diabetes, Obesity And Metabolism, 2020; 23(3): 870-874.
24. SHI S, et al. Association of Cardiac Injury with Mortality in Hospitalized Patients with COVID-19 in Wuhan, China. Jama Cardiology, 2020; 5(7): 802.
25. SINGH AK, et al. Diabetes in COVID-19: prevalence, pathophysiology, prognosis and practical considerations. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 2020; 14(4): 303-310.
26. USHER K, et al. Life in the pandemic: social isolation and mental health. Journal Of Clinical Nursing, 2020; 29(15-16): 2756-2757.
27. VAIRA LA, et al. Anosmia and Ageusia: common findings in covid ⠰19 patients. The Laryngoscope, 2020; 130(7): 1787-1787.
28. VAN DOREMALEN N, et al. Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1. New England Journal Of Medicine, 2020; 382(16): 1564-1567.
29. WANG D, et al. Clinical Characteristics of 138 Hospitalized Patients with 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China. JAMA, 2020; 323(11): 1061–1069.
30. WEI Y, et al. Comprehensive estimation for the length and dispersion of COVID-19 incubation period: a systematic review and meta-analysis. Infection, 2021; 1-11.
31. YUAN J, et al. The correlation between viral clearance and biochemical outcomes of 94 COVID-19 infected discharged patients. Inflammation Research, 2020; 69(6): 599-606.
32. ZHENG YY, et al. COVID-19 and the cardiovascular system. Nat Rev Cardiol., 2020; 17: 259–260.
33. DANIELSEN AC, et al. Sex disparities in COVID-19 outcomes in the United States: quantifying and contextualizing variation. Social Science & Medicine, 2022; 294: 114716.
34. TAKANASHI T, et al. Sex differences in immune responses that underlie COVID-19 disease outcomes. Nature, 2020; 588: 315–320.