Gangrena de Fournier: revisão sobre o diagnóstico e a fisiopatologia
##plugins.themes.bootstrap3.article.main##
Resumo
Objetivo: Descrever a fisiopatologia e o diagnóstico da Gangrena de Fournier (GF). Revisão bibliográfica: Os pacientes com GF, geralmente, desenvolvem infecções de tecidos moles do escroto, regiões perineal e perianal, frequentemente, acompanhadas de edema, eritema, crepitação ou necrose. O fator de risco mais frequente é o Diabetes Mellitus (DM) com uma chance de desenvolver GF três vezes maior. O diagnóstico se dá, principalmente, pela história clínica e exame físico apropriado. Não há exames laboratoriais ou de imagem específicos para o diagnóstico da GF. O tratamento do paciente com GF envolve, essencialmente, a ressuscitação volêmica, a antibioticoterapia de amplo espectro e o desbridamento cirúrgico. Considerações finais: A GF é uma fasciite necrosante rara das regiões perineal, genital ou perianal e que necessita de rápido diagnóstico e tratamento, visto que pode evoluir rapidamente para disfunção de múltiplos órgãos e morte. A apresentação clínica é complexa podendo alterar-se dependendo da progressão da infecção e de características clínicas do paciente. Desse modo, a coleta de uma boa história clínica, a realização de um adequado exame físico e o entendimento da fisiopatologia da doença são fundamentais para o diagnóstico e tratamento precoces, podendo atenuar, assim, a alta taxa de letalidade desta doença.
##plugins.themes.bootstrap3.article.details##
Copyright © | Todos os direitos reservados.
A revista detém os direitos autorais exclusivos de publicação deste artigo nos termos da lei 9610/98.
Reprodução parcial
É livre o uso de partes do texto, figuras e questionário do artigo, sendo obrigatória a citação dos autores e revista.
Reprodução total
É expressamente proibida, devendo ser autorizada pela revista.
Referências
2. AUERBACH J, et al. Fournier Gangrene in the Emergency Department: Diagnostic Dilemmas, Treatments and Current Perspectives. Open Access Emergency Medicine: OAEM, 2020; 12(1): 353–364.
3. BALLARD DH, et al. Fournier Gangrene in Men and Women: Appearance on CT, Ultrasound, and MRI and What the Surgeon Wants to Know. Canadian Association of Radiologists Journal, 2020; 71(1): 30–39.
4. BOUGHANMI F, et al. Fournier’s gangrene: its management remains a challenge. The Pan African Medical Journal, 2021; 38(23).
5. CHERNYADYEV SA, et al. Fournier’s Gangrene: Literature Review and Clinical Cases. Urologia Internationalis, 2018; 101(1): 91-97.
6. CHOWDHURY T, et al. Fournier’s Gangrene: A Coexistence or Consanguinity of SGLT-2 Inhibitor Therapy. Cureus, 2022; 14(8): e27773.
7. ÇALIŞKAN S, et al. Fournier’s gangrene: Review of 36 cases. Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery: TJTES, 2019; 25(5): 479-483.
8. EL-QUSHAYRI AE, et al. Fournier’s gangrene mortality: A 17-year systematic review and meta-analysis. International Journal of Infectious Diseases, 2020; 92: 218-225.
9. FLORES-GALVÁN KP, et al. Gangrena de Fournier. Cirujano General, 2021; 43(2): 107–114.
10. GADLER T, et al. Recognizing Fournier’s gangrene in the emergency department. Adv Emerg Nurs J, 2019; 41(1): 33-38.
11. HOESL V, et al. The LRINEC Score – An Indicator for the Course and Prognosis of Necrotizing Fasciitis?. Journal of Clinical Medicine, 2022; 11 (13): 3583.
12. HUAYLLANI MT, et al. Practical Review of the Current Management of Fournier’s Gangrene. Plastic and Reconstructive Surgery Global Open, 2022; 10(3): e4191.
13. KOCH GE, JOHNSEN NV. The Diagnosis and Management of Life-threatening Urologic Infections. Urology, 2021; 156: 6-15.
14. LARSEN K, et al. Fournier’s gangrene mimicking an acute epididymitis. SAGE Open Medical Case Reports, 2021; 9: 1-3.
15. LEWIS GD, et al. Fournier’s Gangrene Diagnosis and Treatment: A Systematic Review. Cureus, 2021; 13(10): e18948.
16. LOPES LC e LOPES FILHO R. Aplicação do ultrassom point of care e relevância da anatomia na fasciite necrosante. Revista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Sugery, 2022; 37(1).
17. MANJUNATH AS e HOFER MD. Urologic Emergencies. Medical Clinics of North America, 2018; 102(2): 373-385.
18. MONTRIEF T, et al. Fournier Gangrene: A Review for Emergency Clinicians. Journal of Emergency Medicine, 2019; 57(4): 488–500.
19. PROVENZANO D, et al. Fournier’s gangrene as a rare complication in patient with uncontrolled type 2 diabetes treated with surgical debridement: A case report and literature review. International Journal of Surgery Case Reports, 2021; 79: 462–465.
20. RAIZANDHA MA, et al. The role of hyperbaric oxygen therapy in Fournier’s Gangrene: A systematic review and meta-analysis of observational studies. International braz j urol, 2022; 48(5): 771-781.
21. SELVI I, et al. A different perspective for morbidity related to Fournier’s gangrene: which scoring system is more reliable to predict requirement of skin graft and flaps in survivors of Fournier’s gangrene? International Urology and Nephrology, 2019; 51(8): 1303-1311.
22. SINGH A, et al. Fournier’s gangrene. A clinical review. Archivio Italiano di Urologia e Andrologia, 2016; 88(3): 157.
23. ST-LOUIS E, et al. Using the age-adjusted Charlson comorbidity index to predict outcomes in emergency general surgery. The Journal of Trauma and Acute Care Surgery, 2015; 78(2): 318-323.
24. SUMISŁAWSKI P, et al. Utility of Diagnostic Imaging in the Early Detection and Management of the Fournier Gangrene. Diagnostics, 2022; 12(10): 2320.
25. SWEET DE, et al. Imaging of the acute scrotum: keys to a rapid diagnosis of acute scrotal disorders. Abdominal Radiology, 2020; 45(7): 2063–2081.
26. TENÓRIO CEL, et al. Risk factors for mortality in fournier’s gangrene in a general hospital: use of simplified founier gangrene severe index score (SFGSI). International Brazilian Journal of Urology: official journal of the Brazilian Society of Urology, 2018; 44(1): 95-101.
27. VOELZKE BB e HAGEDORN JC. Presentation and Diagnosis of Fournier Gangrene. Urology, 2018; 114: 8-13.
28. WETTERAUER C, et al. A contemporary case series of Fournier’s gangrene at a Swiss tertiary care centercan scoring systems accurately predict mortality and morbidity? World J Emerg Surg, 2018; 13: 25-29.
29. WONGWAISAYAWAN S, et al. Fournier gangrene: pictorial review. Abdominal Radiology (New York), 2020; 45(11): 3838-3848.
30. YILMAZLAR T, et al. Fournier’s gangrene: an analysis of 80 patients and a novel scoring system. Techniques in Coloproctology, 2010; 14(3): 217-223.
31. ZHANG K-F, et al. Progress in Multidisciplinary Treatment of Fournier’s Gangrene. Infection and Drug Resistance, 2022; 15: 6869–6880.