Efeitos do jejum intermitente na saúde humana
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Publicado
Jun 25, 2023
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Resumo
Objetivo: Descrever quais são os efeitos do jejum intermitente à saúde humana. Métodos: Revisão integrativa com recorte temporal entre 2018 a 2022. Utilizou-se como questão norteadora da pesquisa: Quais os efeitos do jejum intermitente à saúde humana? O levantamento bibliográfico ocorreu de junho a julho de 2022, as buscas foram realizadas nas bases de dados SCIELO, LILACS, MEDLINE e PUBMED, por meio dos descritores: Jejum Intermitente; Restrição Alimentar; Restrição Calórica; Comportamento Alimentar. Resultados: Foram selecionados 64 artigos. Deste total, foram excluídos: 4 por duplicidade e 48 por não atender os critérios. A amostra final totalizou 12 artigos, expostos através de quadros. Considerações finais: O jejum intermitente apresentou vantagens em perda de peso, melhora metabólica, diminuição da resistência à insulina e diminuição de resposta inflamatória. O número de estudos do tipo clínico foi bastante reduzido nos últimos cinco anos, portanto, são necessários mais estudos para avaliar a eficiência e segurança do jejum intermitente.
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Como Citar
RibeiroW. A., BorgesL. S. dos S., & LocatelliC. (2023). Efeitos do jejum intermitente na saúde humana. Revista Eletrônica Acervo Saúde, 23(6), e12836. https://doi.org/10.25248/reas.e12836.2023
Seção
Revisão Bibliográfica
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Referências
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16. JONES R, et al. Two weeks of early time-restricted feeding (eTRF) improves skeletal muscle insulin and anabolic sensitivity in healthy men. The American journal of clinical nutrition, 2020, 112(4): 1015-1028.
17. JANG DI, et al. O papel do fator de necrose tumoral alfa (TNF-α) na doença autoimune e os atuais inibidores de TNF-α na terapêutica. Revista Internacional de Ciências Moleculares, 2021, 22(5): 2719.
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22. MARTINEZ BP, et al. Sarcopenia em idosos: um estudo de revisão. Revista Pesquisa em Fisioterapia, 2014, 4(1): 62-70.
23. O'CONNOR SG, et al. Perspective: time-restricted eating compared with caloric restriction: potential facilitators and barriers of long-term weight loss maintenance. Advances in Nutrition, 2021, 12(2): 325-333.
24. OMS. Obesity and overweight. 2021. Disponível https://www.who.int/en/news-room/fact-sheets/detail/obesity-and-overweight. Acessado em: 22 de agosto de 2020.
25. PETERS U, el at. Obesity and asthma. Journal of Allergy and Clinical immunology, 2018, 141(4): 1169-1179.
26. PINHEIRO IL, et al. Perinatal serotonergic activity: A decisive factor in the control of food intake. Revista de Nutrição, 2017, 30: 535-544.
27. RAZAVI R, et al. The alternate-day fasting diet is a more effective approach than a calorie restriction diet on weight loss and hs-CRP levels. International Journal for Vitamin and Nutrition Research, 2021.
28. SILVA VO e BATISTA AS. Efeitos do jejum intermitente para o tratamento da obesidade: uma revisão de literatura. Revista Da Associação Brasileira De Nutrição-RASBRAN, 2021, 12(1) (2021): 164-178.
29. STEKOVIC S, et al. O jejum em dias alternados melhora os marcadores fisiológicos e moleculares do envelhecimento em humanos saudáveis e não obesos. Metabolismo celular, 2019, 30(3): 462-476.
30. SWARUP S, et al. Metabolic Syndrome. StatPearls, 2022, PMID: 29083742.
31. TEONG XT, et al. Eight weeks of intermittent fasting versus calorie restriction does not alter eating behaviors, mood, sleep quality, quality of life and cognitive performance in women with overweight. Nutrition Research, 2021, 92: 32-39.
32. TREPANOWSKI J, et al. Effects of alternate-day fasting or daily calorie restriction on body composition, fat distribution, and circulating adipokines: Secondary analysis of a randomized controlled trial. Clinical Nutrition, 2018, 37(6): 1871-1878.
33. VASIM I e DEBOER MD. Intermittent Fasting and Metabolic Health. Nutrients, 2022, 14(3): 631.
34. WOLFE RR. Branched-chain amino acids and muscle protein synthesis in humans: myth or reality?. Journal of the International Society of Sports Nutrition, 2017, 14(1): 30.
2. BEAULIEU K, et al. Matched weight loss through intermittent or continuous energy restriction does not lead to compensatory increases in appetite and eating behavior in a randomized controlled trial in women with overweight and obesity. The Journal of nutrition, 2020, 150(3): 623-633.
3. CHEN GC, et al. Association between regional body fat and cardiovascular disease risk among postmenopausal women with normal body mass index. European heart journal, 2019, 40(34): 2849-2855.
4. CONLEY M, et al. Is two days of intermittent energy restriction per week a feasible weight loss approach in obese males? A randomised pilot study. Nutrition & Dietetics, 2018, 75(1): 65-72.
5. COSTELLO KR e DUSTIN ES. Chromatin modifications in metabolic disease: Potential mediators of long‐term disease risk. Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2018, 10(4): e1416.
6. DEBENEDICTIS JN, et al. Changes in the homeostatic appetite system after weight loss reflect a normalization toward a lower body weight. The Journal of Clinical Endocrinology & Metabolism, 2020, 105(7): e2538-e2546.
7. FARIA RC, et al. Dietary recommendations during the COVID-19 pandemic. Nutrition reviews, 2021, 79(4): 382-393.
8. FOSTER JA, et al. Stress & the gut-brain axis: regulation by the microbiome. Neurobiology of stress, 2017, 7: 124-136.
9. GUIMARÃES BP, et al. O consumo de água em idosos: uma revisão. Vita et Sanitas, 2021, 15(2): 53-69.
10. GABEL K, et al. Differential effects of alternate-day fasting versus daily calorie restriction on insulin resistance. Obesity, 2019, 27(9): 1443-1450.
11. GAO Y, et al. Effects of intermittent (5: 2) or continuous energy restriction on basal and postprandial metabolism: A randomised study in normal-weight, young participants. European journal of clinical nutrition, 2022, 76(1): 65-73.
12. GISTERÅ A, et al. Low-density lipoprotein-reactive T cells regulate plasma cholesterol levels and development of atherosclerosis in humanized hypercholesterolemic mice. Circulation, 2018, 138(22): 2513-2526.
13. HALPERN B e MENDES TB. J Intermittent fasting for obesity and related disorders: unveiling myths, facts, and presumptions. Archives of Endocrinology and Metabolism, 2021, 65: 14-23.
14. HAN K, et al. A pilot study to investigate the immune-modulatory effects of fasting in steroid-naive mild asthmatics. The Journal of Immunology, 2018, 201(5): 1382-1388.
15. INADA LH, et al. Dietas da moda: aspectos comparativos e nocivos ao organismo-uma revisão bibliográfica. Revista Higei@-Revista Científica de Saúde, 2021, 3(6).
16. JONES R, et al. Two weeks of early time-restricted feeding (eTRF) improves skeletal muscle insulin and anabolic sensitivity in healthy men. The American journal of clinical nutrition, 2020, 112(4): 1015-1028.
17. JANG DI, et al. O papel do fator de necrose tumoral alfa (TNF-α) na doença autoimune e os atuais inibidores de TNF-α na terapêutica. Revista Internacional de Ciências Moleculares, 2021, 22(5): 2719.
18. LEVINE B e KLIONSKY DJ. Autophagy wins the 2016 Nobel Prize in Physiology or Medicine: Breakthroughs in baker's yeast fuel advances in biomedical research. Proceedings of the National Academy of Sciences, 2017, 114 (2): 201-205.
19. LIN S, et al. Does the weight loss efficacy of alternate day fasting differ according to sex and menopausal status?. Nutrition, Metabolism and Cardiovascular Diseases, 2021, 31(2): 641-649.
20. LOBSTEIN T, et al. World Obesity Atlas. 2022. Disponível https://policycommons.net/artifacts/2266990/world_obesity_atlas_2022_web/3026660/em 21 de novembro de 2022. CID: 20.500.12592/74dsjp. Acessado em: 01 de setembro de 2020.
21. MANDAL S, et al. Jejum intermitente: comer de acordo com o relógio para melhorar a saúde e o desempenho dos exercícios. BMJ Open Sport & Exercise Medicine, 2022; 8(1): e001206.
22. MARTINEZ BP, et al. Sarcopenia em idosos: um estudo de revisão. Revista Pesquisa em Fisioterapia, 2014, 4(1): 62-70.
23. O'CONNOR SG, et al. Perspective: time-restricted eating compared with caloric restriction: potential facilitators and barriers of long-term weight loss maintenance. Advances in Nutrition, 2021, 12(2): 325-333.
24. OMS. Obesity and overweight. 2021. Disponível https://www.who.int/en/news-room/fact-sheets/detail/obesity-and-overweight. Acessado em: 22 de agosto de 2020.
25. PETERS U, el at. Obesity and asthma. Journal of Allergy and Clinical immunology, 2018, 141(4): 1169-1179.
26. PINHEIRO IL, et al. Perinatal serotonergic activity: A decisive factor in the control of food intake. Revista de Nutrição, 2017, 30: 535-544.
27. RAZAVI R, et al. The alternate-day fasting diet is a more effective approach than a calorie restriction diet on weight loss and hs-CRP levels. International Journal for Vitamin and Nutrition Research, 2021.
28. SILVA VO e BATISTA AS. Efeitos do jejum intermitente para o tratamento da obesidade: uma revisão de literatura. Revista Da Associação Brasileira De Nutrição-RASBRAN, 2021, 12(1) (2021): 164-178.
29. STEKOVIC S, et al. O jejum em dias alternados melhora os marcadores fisiológicos e moleculares do envelhecimento em humanos saudáveis e não obesos. Metabolismo celular, 2019, 30(3): 462-476.
30. SWARUP S, et al. Metabolic Syndrome. StatPearls, 2022, PMID: 29083742.
31. TEONG XT, et al. Eight weeks of intermittent fasting versus calorie restriction does not alter eating behaviors, mood, sleep quality, quality of life and cognitive performance in women with overweight. Nutrition Research, 2021, 92: 32-39.
32. TREPANOWSKI J, et al. Effects of alternate-day fasting or daily calorie restriction on body composition, fat distribution, and circulating adipokines: Secondary analysis of a randomized controlled trial. Clinical Nutrition, 2018, 37(6): 1871-1878.
33. VASIM I e DEBOER MD. Intermittent Fasting and Metabolic Health. Nutrients, 2022, 14(3): 631.
34. WOLFE RR. Branched-chain amino acids and muscle protein synthesis in humans: myth or reality?. Journal of the International Society of Sports Nutrition, 2017, 14(1): 30.