Câncer de mama masculino: um relato de caso

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Ivan Rodrigues Silva
Andressa Carvalho Pereira
Pedro Henrique dos Santos Silva
Carlos Antônio Soares de Sousa Filho
Maria Beatriz Pereira de Paula Rocha
Franciele Basso Fernandes Silva

Resumo

Objetivo: Este artigo tem como objetivo relatar um caso de câncer de mama em um paciente do sexo masculino, que também apresentava síndrome de lise tumoral e suspeita de metástase para calota craniana. Detalhamento do caso: O presente estudo relata o caso de um paciente do sexo masculino, 77 anos, sem histórico familiar de câncer, que apresentava ginecomastia e massa irregular na região infra-axilar, com degeneração cística central, classificada como BIRADS IV-A. O paciente evoluiu com síndrome de lise tumoral e com múltiplas lesões ósseas líticas espalhadas pelo crânio, com possibilidade de acometimento neoplásico secundário. Considerações finais: O câncer de mama em homens geralmente é diagnosticado em estágios mais avançados e geralmente é tratado de acordo com os procedimentos recomendados para o câncer de mama feminino. É importante compreender a doença e as suas manifestações clínicas, bem como do aumento da conscientização sobre esse tipo de câncer no homem. Ademais, mais estudos sobre opções terapêuticas específicas para o câncer de mama masculino são necessários, a fim de estabelecer um padrão de atendimento baseado em evidências para essa população.

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Como Citar
SilvaI. R., PereiraA. C., SilvaP. H. dos S., Sousa FilhoC. A. S. de, RochaM. B. P. de P., & SilvaF. B. F. (2023). Câncer de mama masculino: um relato de caso. Revista Eletrônica Acervo Saúde, 23(8), e13606. https://doi.org/10.25248/reas.e13606.2023
Seção
Estudos de Caso

Referências

1. ABDELWAHAB YOUSEF AJ. Male Breast Cancer: Epidemiology and Risk Factors. Seminars in Oncology, 2017; 44(4): 267–272.

2. AMERICAN CANCER SOCIETY. 2023. Cancer Facts & Figures 2023. Disponível em: https://www.cancer.org/research/cancer-facts-statistics/all-cancer-facts-figures/2023-cancer-facts-figures.html. Acessado em: 26 de março de 2023.

3. ARAUJO SEA, et al. Impact of COVID-19 pandemic on care of oncological patients: experience of a cancer center in a Latin American pandemic epicenter. Einstein (Sao Paulo), 2020; 19: eAO6282.

4. BARBAR T, JAFFER SATHICK I. Tumor Lysis Syndrome. Advances in Chronic Kidney Disease, 2021; 28(5): 438- 446.e1.

5. BOZOVICH GE, et al. Daño colateral de la pandemia por COVID-19 en centros privados de salud de Argentina. Medicina (B. Aires), 2020; 80(3): 37–41.

6. BRINTON LA, et al. Prospective Evaluation of Risk Factors for Male Breast Cancer. JNCI Journal of the National Cancer Institute, 2008; 100(20): 1477–1481.

7. CARVALHO HDEA, et al. Impact of COVID-19 pandemic on a daily-based outpatient treatment routine: experience of a radiotherapy department of a tertiary public/university hospital in Brazil. Clinics (Sao Paulo, Brazil), 2020; 75: e2298.

8. DALY MB, et al. Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network: JNCCN, 2021; 19(1): 77–102.

9. DING YC, et al. Mutations in BRCA2 and PALB2 in male breast cancer cases from the United States. Breast Cancer Research and Treatment, 2011; 126(3): 771–778.

10. EL OMARI-ALAOUI H, et al. Male breast cancer. A report of 71 cases. Cancer Radiotherapie: Journal De La Societe Francaise De Radiotherapie Oncologique, 2002; 6(6): 349–351.

11. ELBACHIRI M, et al. Cancer du sein chez l’homme: à propos de 40 cas et revue de la littérature. The Pan African Medical Journal, 2017; 28: 287.

12. EXPERT PANEL ON BREAST IMAGING, et al. ACR Appropriateness Criteria® Evaluation of the Symptomatic Male Breast. Journal of the American College of Radiology: JACR, 2018; 15(11S): S313–S320.

13. FARIA RA, et al. Carcinoma de mama masculino: um relato de caso / Male breast carcinoma: a case report. Brazilian Journal of Health Review, 2020; 3(1): 78–95.

14. FELETTO E, et al. How has COVID-19 impacted cancer screening? Adaptation of services and the future outlook in Australia. Public Health Research & Practice, 2020; 30(4): 3042026.

15. GILBERT SF, et al. Clinical profile, BRCA2 expression, and the androgen receptor CAG repeat region in Egyptian and Moroccan male breast cancer patients. Breast Disease, 2011; 33(1): 17–26.

16. GUCALP A, et al. Male breast cancer: a disease distinct from female breast cancer. Breast Cancer Research and Treatment, 2019; 173(1): 37–48.

17. HANDY C, et al. Tumor lysis Syndrome in a Patient with Metastatic Breast Cancer Treated with Alpelisib. Breast Cancer: Basic and Clinical Research, 2021; 15: 11782234211037420.

18. HASSETT MJ, et al. Management of Male Breast Cancer: ASCO Guideline. Journal of Clinical Oncology, 2020; 38(16): 1849–1863.

19. INSTITUTO NACIONAL DE CÂNCER. Estimativa 2023: incidência de câncer no Brasil. 2022. Disponível em: https://www.inca.gov.br/publicacoes/livros/estimativa-2023-incidencia-de-cancer-no-brasil. Acessado em: 26 de março de 2023.

20. KAKHKI VRD, et al. Pattern and distribution of bone metastases in common malignant tumors. Nuclear Medicine Review. Central & Eastern Europe, 2013; 16(2): 66–69.

21. KHAN NAJ, TIRONA M. An updated review of epidemiology, risk factors, and management of male breast cancer. Medical Oncology, 2021; 38(4): 39.

22. KONDURI S, et al. Epidemiology of male breast cancer. The Breast: Official Journal of the European Society of Mastology, 2020; 54: 8–14.

23. MAKDISSI FBA, et al. An introduction to male breast cancer for urologists: epidemiology, diagnosis, principles of treatment, and special situations. International Brazilian Journal of Urology: Official Journal of the Brazilian Society of Urology, 2022; 48(5): 760–770.

24. METHAMEM M, et al. Breast cancer in men: a serie of 45 cases and literature review. The Pan African Medical Journal, 2020; 36: 183.

25. NOFAL MN, YOUSEF AJ. The diagnosis of male breast cancer. The Netherlands Journal of Medicine, 2019; 77(10): 356-359.

26. PEREIRA CU, MELO MS. Metástases cranianas: considerações sobre 21 casos. Arq Bras Neurocir, 2009; 28(3): 97-102.

27. RUDDY KJ, WINER EP. Male breast cancer: risk factors, biology, diagnosis, treatment, and survivorship. Annals of Oncology: Official Journal of the European Society for Medical Oncology, 2013; 24(6): 1434–1443.

28. SERDY K M, et al. Male Breast Cancer: A Single-Institution Clinicopathologic and Immunohistochemical Study. American Journal of Clinical Pathology, 2017; 147(1): 110–119.

29. SKLARIN NT, MARKHAM M. Spontaneous Recurrent Tumor Lysis Syndrome in Breast Cancer: American Journal of Clinical Oncology, 1995; 18(1): 71–73.

30. STARK AM, et al. Skull metastases: clinical features, differential diagnosis, and review of the literature. Surgical Neurology, 2003; 60(3): 219–225.

31. ZAJĄCZKOWSKA R, et al. Bone Pain in Cancer Patients: Mechanisms and Current Treatment. International Journal of Molecular Sciences, 2019; 20(23): 6047.

32. ZEHR KR. Diagnosis and Treatment of Breast Cancer in Men. Radiologic Technology, 2019; 91(1): 51M-61M.