Associações entre a alimentação e o risco de câncer colorretal
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Publicado
Apr 18, 2024
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Resumo
Objetivo: Discutir a relação entre a alimentação e o câncer colorretal. Métodos: Revisão integrativa da literatura sobre a associação entre alimentação e câncer colorretal (CCR). Foram selecionados 38 artigos nos últimos cinco anos a partir das bases de dados PubMed e BVS. Foram incluídos estudos do tipo experimental, ensaios clínicos, caso-controle e coorte. Resultados: Essa pesquisa evidenciou a relação entre de CCR e a dieta habitual de indivíduos. O excesso de carnes vermelhas e processadas foi associado ao aumento do risco da neoplasia, enquanto dietas ricas em vegetais mostraram efeitos protetores. A microbiota intestinal desempenhou um papel importante no desenvolvimento da doença, e esta, sofre a influência significativa da dieta. Probióticos como Lactobacillus fermentum ME-3 exibe potencial preventivo nesta neoplasia, devido aos seus efeitos antioxidantes e anti-inflamatórios, fortalecendo o microbioma. Os miRNAs, como o miR-144, são essenciais na regulação do metabolismo em pacientes com CCR, afetando o gene mTOR e destaca a importância da dieta na redução do risco do tumor. Considerações finais: O consumo excessivo de carne vermelha e de alimentos ultraprocessados contribui para alterações da microbiota intestinal e um maior risco de CCR.
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Como Citar
RibeiroS. de L., SantosM. S. C. dos, OliveiraB. M. de, MoraisA. J. A. de, PassosX. S., & AraújoC. C. de. (2024). Associações entre a alimentação e o risco de câncer colorretal. Revista Eletrônica Acervo Saúde, 24(4), e15210. https://doi.org/10.25248/reas.e15210.2024
Seção
Revisão Bibliográfica
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Referências
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2. BOUVARD V, et al. Carcinogenicity of consumption of red and processed meat. The Lancet Oncology, 2015; 16(1): 1599-1600.
3. BRAVI F, et al. Adherence to the World Cancer Research Fund/American Institute for Cancer Research recommendations and head and neck cancers risk. Oral Oncology, 2017; 64(1): 59-64.
4. BREMER FP, et al. Os imunomarcadores CDX2, beta-catenina e WNT são úteis para avaliar a chance de progressão de doença ou a evolução para óbito em pacientes com câncer colorretal? Arquivos Brasileiros de Cirurgia Digestiva, 2020; 33(3): 1-4.
5. BULTMAN SJ. Molecular pathways: Gene-environment interactions regulating dietary fiber induction of proliferation and apoptosis via butyrate for cancer prevention. Clinical Cancer Research, 2014; 20(4): 799-803.
6. CROSS AJ e SINHA R. Meat-related mutagens/carcinogens in the etiology of colorectal cancer. Environmental and Molecular Mutagenesis, 2004; 44(1): 44-55.
7. DECLERCQ V, et al. Plant-Based Diets and Cancer Risk: What is the Evidence? Current Nutrition Reports, 2022; 11(2): 354-69.
8. DIALLO AK, et al. Association between a pro plant-based dietary score and cancer risk in the prospective NutriNet-santé cohort. International Journal of Cancer, 2018; 143(9): 2168-2176.
9. FERLAY J, et al. Cancer statistics for the year 2020: An overview. International Journal of Cancer, 2021; 149(4): 778-789.
10. GONG, L. et al. Whole cereal grains and potential health effects: Involvement of the gut microbiota. Food Research International, 2018; 103(4): 84-102.
11. GU MJ, et al. Attributable causes of colorectal cancer in China. BMC Cancer, 2018; 18(38): 1-9.
12. INCA. 2022. Ministério da saúde. Estima 704 mil casos de câncer por ano no Brasil até 2025. Disponível em: https://www.gov.br/inca/pt-br/assuntos/noticias/2022/inca-estima-704-mil-casos-de-cancer-por-ano-no-brasil-ate-2025. Acessado em: 26 de setembro de 2023.
13. ISLAMI F, et al. Proportion and number of cancer cases and deaths attributable to potentially modifiable risk factors in the United States. CA: A Cancer Journal for Clinicians, 2018; 68(1): 31-54.
14. KEUM N e GIOVANNUCCI E. Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies. Nature Reviews Gastroenterology and Hepatology, 2019; 16(12): 713-732.
15. KHODAII Z, et al. Novel targets in rectal cancer by considering lncRNA–miRNA–mRNA network in response to Lactobacillus acidophilus consumption: a randomized clinical trial. Scientific Reports, 2022; 12(1): 1-18.
16. KIM JY, et al. Different risk factors for advanced colorectal neoplasm in young adults. World Journal of Gastroenterology, 2016; 22(13): 3611-3620.
17. LIU PH, et al. Association of Obesity with Risk of Early-Onset Colorectal Cancer among Women. JAMA Oncology, 2019; 5(1): 37-44.
18. LIU Y, et al. Dietary quality and the colonic mucosa-associated gut microbiome in humans. American Journal of Clinical Nutrition, 2019; 110(3): 701-712.
19. LIZ S, et al. Adherence to the WCRF/AICR for Women in Breast Cancer Adjuvant Treatment submitted to Educational Nutritional Intervention. Nutrition and Cancer, 2018; 70(5): 737-747.
20. MOHAMMAD NMAB, et al. Association between Diet-related Behaviour and Risk of Colorectal Cancer. Journal of Cancer Prevention, 2022; 27(4): 208-220.
21. OLIVEIRA MM, et al. Disparidades na mortalidade de câncer colorretal nos estados brasileiros. Revista Brasileira de Epidemiologia, 2018; 21(1): 1-14.
22. PARR CL, et al. Meat intake, cooking methods and risk of proximal colon, distal colon and rectal cancer: The Norwegian Women and Cancer (NOWAC) cohort study. International Journal of Cancer, 2013; 133(5): 1153-1163.
23. ROSATO V, et al. Risk factors for young-onset colorectal cancer. Cancer Causes and Control, 2013; 24(2): 335-341.
24. SATIJA A, et al. Healthful and Unhealthful Plant-Based Diets and the Risk of Coronary Heart Disease in U.S. Adults. Journal of the American College of Cardiology, 2017; 70(4): 411-422.
25. SEPP E, et al. The effect of Lactobacillus fermentum ME-3 on the intestinal microbiota and urine polyamines content: A double-blind placebo-controlled pilot trial. Journal of Functional Foods, 2018; 48(1): 430-438.
26. SHEN W, et al. Food intake and its effect on the species and abundance of intestinal flora in colorectal cancer and healthy individuals. Korean Journal of Internal Medicine, 2021; 36(3): 568-583.
27. SHIELD KD, et al. New cancer cases attributable to diet among adults aged 30-84 years in France in 2015. British Journal of Nutrition, 2018; 120(10): 1171-1180.
28. SONG M e CHAN AT. Environmental Factors, Gut Microbiota, and Colorectal Cancer Prevention. Clinical Gastroenterology and Hepatology, 2019; 17(2): 275-289.
29. SUNG H, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 2021; 71(3): 209-249.
30. THANIKACHALAM K e KHAN G. Colorectal cancer and nutrition. Nutrients, 2019; 11(1): 1-11.
31. THARREY M, et al. Patterns of plant and animal protein intake are strongly associated with cardiovascular mortality: The Adventist Health Study-2 cohort. International Journal of Epidemiology, 2018; 47(5): 1603-1612.
32. TORRES AEC e VÉLEZ YEF. Influencias de alimentos, sedentarismo y estrés en la prevención del cáncer colorrectal. Revista de Salud Pública, 2019; 23(2): 53-68.
33. VERNIA F, et al. Dietary Factors Modulating Colorectal Carcinogenesis. Nutrients, 2021; 13(1): 1-13.
34. VUIK FER, et al. Increasing incidence of colorectal cancer in young adults in Europe over the last 25 years. Gut, 2019; 68(1): 1820-1826.
35. WATANABE D, et al. Association between dietary intake and the prevalence of tumourigenic bacteria in the gut microbiota of middle-aged Japanese adults. Scientific Reports, 2020; 10(1): 1-10.
36. YACHIDA S, et al. Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer. Nature Medicine, 2019; 25(6): 968-976.
37. YUAN C e SUBRAMANIAN S. MicroRNA-Mediated Tumor-Microbiota Metabolic Interactions in Colorectal Cancer. DNA and Cell Biology, 2019; 38(4): 281-285.
38. ZHENG X, et al. Comprehensive Assessment of Diet Quality and Risk of Precursors of Early-Onset Colorectal Cancer. Journal Natl Cancer Institution, 2021; 113(5): 543-552.
2. BOUVARD V, et al. Carcinogenicity of consumption of red and processed meat. The Lancet Oncology, 2015; 16(1): 1599-1600.
3. BRAVI F, et al. Adherence to the World Cancer Research Fund/American Institute for Cancer Research recommendations and head and neck cancers risk. Oral Oncology, 2017; 64(1): 59-64.
4. BREMER FP, et al. Os imunomarcadores CDX2, beta-catenina e WNT são úteis para avaliar a chance de progressão de doença ou a evolução para óbito em pacientes com câncer colorretal? Arquivos Brasileiros de Cirurgia Digestiva, 2020; 33(3): 1-4.
5. BULTMAN SJ. Molecular pathways: Gene-environment interactions regulating dietary fiber induction of proliferation and apoptosis via butyrate for cancer prevention. Clinical Cancer Research, 2014; 20(4): 799-803.
6. CROSS AJ e SINHA R. Meat-related mutagens/carcinogens in the etiology of colorectal cancer. Environmental and Molecular Mutagenesis, 2004; 44(1): 44-55.
7. DECLERCQ V, et al. Plant-Based Diets and Cancer Risk: What is the Evidence? Current Nutrition Reports, 2022; 11(2): 354-69.
8. DIALLO AK, et al. Association between a pro plant-based dietary score and cancer risk in the prospective NutriNet-santé cohort. International Journal of Cancer, 2018; 143(9): 2168-2176.
9. FERLAY J, et al. Cancer statistics for the year 2020: An overview. International Journal of Cancer, 2021; 149(4): 778-789.
10. GONG, L. et al. Whole cereal grains and potential health effects: Involvement of the gut microbiota. Food Research International, 2018; 103(4): 84-102.
11. GU MJ, et al. Attributable causes of colorectal cancer in China. BMC Cancer, 2018; 18(38): 1-9.
12. INCA. 2022. Ministério da saúde. Estima 704 mil casos de câncer por ano no Brasil até 2025. Disponível em: https://www.gov.br/inca/pt-br/assuntos/noticias/2022/inca-estima-704-mil-casos-de-cancer-por-ano-no-brasil-ate-2025. Acessado em: 26 de setembro de 2023.
13. ISLAMI F, et al. Proportion and number of cancer cases and deaths attributable to potentially modifiable risk factors in the United States. CA: A Cancer Journal for Clinicians, 2018; 68(1): 31-54.
14. KEUM N e GIOVANNUCCI E. Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies. Nature Reviews Gastroenterology and Hepatology, 2019; 16(12): 713-732.
15. KHODAII Z, et al. Novel targets in rectal cancer by considering lncRNA–miRNA–mRNA network in response to Lactobacillus acidophilus consumption: a randomized clinical trial. Scientific Reports, 2022; 12(1): 1-18.
16. KIM JY, et al. Different risk factors for advanced colorectal neoplasm in young adults. World Journal of Gastroenterology, 2016; 22(13): 3611-3620.
17. LIU PH, et al. Association of Obesity with Risk of Early-Onset Colorectal Cancer among Women. JAMA Oncology, 2019; 5(1): 37-44.
18. LIU Y, et al. Dietary quality and the colonic mucosa-associated gut microbiome in humans. American Journal of Clinical Nutrition, 2019; 110(3): 701-712.
19. LIZ S, et al. Adherence to the WCRF/AICR for Women in Breast Cancer Adjuvant Treatment submitted to Educational Nutritional Intervention. Nutrition and Cancer, 2018; 70(5): 737-747.
20. MOHAMMAD NMAB, et al. Association between Diet-related Behaviour and Risk of Colorectal Cancer. Journal of Cancer Prevention, 2022; 27(4): 208-220.
21. OLIVEIRA MM, et al. Disparidades na mortalidade de câncer colorretal nos estados brasileiros. Revista Brasileira de Epidemiologia, 2018; 21(1): 1-14.
22. PARR CL, et al. Meat intake, cooking methods and risk of proximal colon, distal colon and rectal cancer: The Norwegian Women and Cancer (NOWAC) cohort study. International Journal of Cancer, 2013; 133(5): 1153-1163.
23. ROSATO V, et al. Risk factors for young-onset colorectal cancer. Cancer Causes and Control, 2013; 24(2): 335-341.
24. SATIJA A, et al. Healthful and Unhealthful Plant-Based Diets and the Risk of Coronary Heart Disease in U.S. Adults. Journal of the American College of Cardiology, 2017; 70(4): 411-422.
25. SEPP E, et al. The effect of Lactobacillus fermentum ME-3 on the intestinal microbiota and urine polyamines content: A double-blind placebo-controlled pilot trial. Journal of Functional Foods, 2018; 48(1): 430-438.
26. SHEN W, et al. Food intake and its effect on the species and abundance of intestinal flora in colorectal cancer and healthy individuals. Korean Journal of Internal Medicine, 2021; 36(3): 568-583.
27. SHIELD KD, et al. New cancer cases attributable to diet among adults aged 30-84 years in France in 2015. British Journal of Nutrition, 2018; 120(10): 1171-1180.
28. SONG M e CHAN AT. Environmental Factors, Gut Microbiota, and Colorectal Cancer Prevention. Clinical Gastroenterology and Hepatology, 2019; 17(2): 275-289.
29. SUNG H, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 2021; 71(3): 209-249.
30. THANIKACHALAM K e KHAN G. Colorectal cancer and nutrition. Nutrients, 2019; 11(1): 1-11.
31. THARREY M, et al. Patterns of plant and animal protein intake are strongly associated with cardiovascular mortality: The Adventist Health Study-2 cohort. International Journal of Epidemiology, 2018; 47(5): 1603-1612.
32. TORRES AEC e VÉLEZ YEF. Influencias de alimentos, sedentarismo y estrés en la prevención del cáncer colorrectal. Revista de Salud Pública, 2019; 23(2): 53-68.
33. VERNIA F, et al. Dietary Factors Modulating Colorectal Carcinogenesis. Nutrients, 2021; 13(1): 1-13.
34. VUIK FER, et al. Increasing incidence of colorectal cancer in young adults in Europe over the last 25 years. Gut, 2019; 68(1): 1820-1826.
35. WATANABE D, et al. Association between dietary intake and the prevalence of tumourigenic bacteria in the gut microbiota of middle-aged Japanese adults. Scientific Reports, 2020; 10(1): 1-10.
36. YACHIDA S, et al. Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer. Nature Medicine, 2019; 25(6): 968-976.
37. YUAN C e SUBRAMANIAN S. MicroRNA-Mediated Tumor-Microbiota Metabolic Interactions in Colorectal Cancer. DNA and Cell Biology, 2019; 38(4): 281-285.
38. ZHENG X, et al. Comprehensive Assessment of Diet Quality and Risk of Precursors of Early-Onset Colorectal Cancer. Journal Natl Cancer Institution, 2021; 113(5): 543-552.