Potencial terapêutico dos canabinoides em doenças neurodegenerativas: Parkinson, Alzheimer e Esclerose Múltipla

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Brenda Winona dos Santos
Idonilton da Conceição Fernandes
Josiane de Fatima Gaspari Dias
Deise Prehs Montrucchio
Luciane Dalarmi
Obdulio Gomes Miguel
Marilis Dallarmi Miguel

Resumo

Objetivo: Analisar sobre os efeitos dos canabinoides no tratamento e/ou alívio de sintomas de doenças neurodegenerativas, como: Parkinson, Doença de Alzheimer e Esclerose Múltipla. Métodos: Foi realizada uma revisão integrativa intencionando compilar os principais resultados do uso dos canabinoides na prevenção e controle de doenças neurodegenerativas com foco nas doenças de Parkinson, Alzheimer e Esclerose Múltipla. Foram selecionados artigos científicos disponíveis no portal Periódicos Capes distribuídos nas bases de dados PubMed, Science Direct e Medline. Resultados: Foram encontrados 331 artigos científicos filtrados apenas para testes clínicos, destes após triagem foram lidos integralmente 52 textos e para esta revisão foram selecionados 21 artigos. Os artigos selecionados demonstram resultados positivos na melhora de sintomas e na qualidade de vida geral em todas as patologias. A maioria dos estudos foram realizados em países europeus, demonstrando a necessidade de maiores investimentos em pesquisas clínicas com canabinoides principalmente na América do Sul. Considerações finais: Com a análise dos textos é possível concluir que os canabinoides Tetra-hidrocanabinol (THC) e Canabidiol (CBD) são compostos benéficos em testes clínicos com resultados positivos no controle e prevenção de sintomas das três doenças neurodegenerativas escolhidas para esta revisão.

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Como Citar
SantosB. W. dos, FernandesI. da C., DiasJ. de F. G., MontrucchioD. P., DalarmiL., MiguelO. G., & MiguelM. D. (2024). Potencial terapêutico dos canabinoides em doenças neurodegenerativas: Parkinson, Alzheimer e Esclerose Múltipla. Revista Eletrônica Acervo Saúde, 24(1), e15296. https://doi.org/10.25248/reas.e15296.2024
Seção
Revisão Bibliográfica

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