Infecção pelo Trichomonas vaginalis em gestantes: patogênese, diagnóstico e tratamento

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Martha Laura Leão dos Santos Silva
Juliana Félix de Melo

Resumo

Objetivo: Reunir informações que abordem as alterações decorrentes da infecção pelo Trichomonas vaginalis em mulheres grávidas. Métodos: Trata-se de uma pesquisa descritiva, qualitativa. A busca de artigos foi feita nas seguintes bases de dados: SCIELO, PUBMED e LILACS, utilizando os descritores: “Saúde da Mulher”; “Tricomoníase”; “Complicações infecciosas na gravidez”. Foram incluídos artigos científicos publicados de janeiro de 2018 a outubro de 2023, em inglês, português e espanhol e que apresentassem conteúdo relevante para o tema. Ao final da análise, restaram 26 artigos para serem incluídos no presente estudo. Resultados: A tricomoníase está associada com resultados adversos no parto. Na rede pública do Brasil, o diagnóstico não é realizado pela identificação do agente etiológico e o manejo ocorre de modo sindrômico. Existem diferentes respostas das mulheres ao mesmo tipo de alteração na microbiota vaginal. Para diagnosticar a doença, métodos por amplificação de ácidos nucleicos fornecem resultados mais precisos e o tratamento é realizado com metronidazol via oral, medicamento seguro na gestação. Considerações finais: É necessário que mais estudos sejam realizados no Brasil para avaliação da necessidade de rastreio de algumas doenças infecciosas em gestantes tais como a tricomoníase.

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Como Citar
SilvaM. L. L. dos S., & MeloJ. F. de. (2024). Infecção pelo Trichomonas vaginalis em gestantes: patogênese, diagnóstico e tratamento. Revista Eletrônica Acervo Saúde, 24(6), e15448. https://doi.org/10.25248/reas.e15448.2024
Seção
Revisão Bibliográfica

Referências

1. AARON KJ, et al. Vaginal Swab vs Urine for Detection ofChlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis: A Meta-Analysis. The Annals of Family Medicine, 2023; 21(2): 172–179.

2. ASRES AW, et al. Prevalence and trends of sexually transmitted infections among pregnant women in Mizan Tepi University Teaching Hospital, Southwest Ethiopia: a cross-sectional study. The Pan African medical jornal, 2022; 42: 111.

3. BAGGA R, ARORA P. Genital Micro-Organisms in Pregnancy. Frontiers in Public Health, 2020; 8: 225.

4. BAQUI AH, et al. Prevalence of and risk factors for abnormal vaginal flora and its association with adverse pregnancy outcomes in a rural district in north-east Bangladesh. Acta obstetricia et gynecologica Scandinavica, 2019; 98(3): 309-319.

5. BRASIL. Ministério da Saúde. Protocolo Clínico e Diretrizes Terapêuticas para Atenção Integral às Pessoas com Infecções Sexualmente Transmissíveis (IST). 2022. Disponível em: https://www.gov.br/aids/pt-br/centrais-de-conteudo/pcdts/2022/ist/pcdt-ist-2022_isbn-1.pdf/view. Acessado em: 5 de outubro de 2023.

6. BRUNHAM RC e PAAVONEN J. Reproductive system infections in women: upper genital tract, fetal, neonatal and infant syndromes. Pathogens and Disease, 2020; 78(5): ftaa023.

7. DIONNE-ODOM J, et al. HIV Status and Other Risk Factors for Prevalent and Incident Sexually Transmitted Infection during Pregnancy (2000-2014). Infectious Diseases in Obstetrics and Gynecology, 2019; 2019: 1-8.

8. GRANT JS, et al. Sexually Transmitted Infections in Pregnancy: A Narrative Review of the Global Research Gaps, Challenges, and Opportunities. Sexually Transmitted Diseases, 2020; 47(12): 779-789.

9. HILLIER SL, et al. Diagnosis and Treatment of Vaginal Discharge Syndromes in Community Practice Settings. Clinical Infectious Diseases, 2020; 72(9): 1538–1543.

10. HUSAIN S, et al. Effects of oral probiotic supplements on vaginal microbiota during pregnancy: a randomised, double-blind, placebo-controlled trial with microbiome analysis. BJOG: an international journal of obstetrics and gynaecology, 2019; 127(2): 275-284.

11. JARRETT OD, et al. Specific Vaginal Bacteria Are Associated With an Increased Risk of Trichomonas vaginalis Acquisition in Women. The Journal of Infectious Diseases, 2019; 220(9): 1503-1510.

12. KALIA N, et al. Microbiota in vaginal health and pathogenesis of recurrent vulvovaginal infections: a critical review. Annals of Clinical Microbiology and Antimicrobials, 2020; 19(1): 5.

13. KIM TG, et al. Trichomonas vaginalis in Pregnancy: Patterns and Predictors of Testing, Infection, and Treatment. Obstetrics & Gynecology, 2020; 135(5): 1136-1144.

14. LEE ACC, et al. Effect of population-based antenatal screening and treatment of genitourinary tract infections on birth outcomes in Sylhet, Bangladesh (MIST): a cluster-randomised clinical trial. The Lancet Global Health, 2019; 7(1): e148–e159.

15. LILLIS RA, et al. Clinical Evaluation of a New Molecular Test for the Detection of Organisms Causing Vaginitis and Vaginosis. Journal of Clinical Microbiology, 2023; 61(3): e0174822.

16. NYEMBA DC, et al. Impact of aetiological screening of sexually transmitted infections during pregnancy on pregnancy outcomes in South Africa. BMC pregnancy and childbirth, 2022; 22(1): 194.

17. ODAGAMI M, et al. Awareness of Infectious Disease Screening During Early Pregnancy and Knowledge About its Vertical Transmission in Japan: A Report from the Pregnant Women Health Initiative. Maternal and Child Health Journal, 2023; 27(5): 933-943.

18. OP DE COUL ELM, et al. Chlamydia trachomatis, Neisseria gonorrhoea, and Trichomonas vaginalis infections among pregnant women and male partners in Dutch midwifery practices: prevalence, risk factors, and perinatal outcomes. Reproductive Health, 2021; 18(1): 132.

19. PALMA C, et al. Cribado de infecciones cervicales de transmisión sexual en mujeres embarazadas y su relación con la microbiota vaginal. Revista chilena de infectología, 2019; 36(3): 292-298.

20. RAJABPOUR M, et al. Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis among women with genitourinary infection and pregnancy-related complications in Tehran: A cross-sectional study. International Journal of STD & AIDS, 2020; 31(8): 773-780.

21. SHANNON CL, et al. Acceptability and Feasibility of Rapid Chlamydial, Gonococcal, and Trichomonal Screening and Treatment in Pregnant Women in 6 Low- to Middle-Income Countries. Sexually transmitted diseases, 2018; 45(10): 673-676.

22. TEASDALE CA, et al. Incidence of sexually transmitted infections during pregnancy. PloS one, 2018; 13(5): e0197696.

23. THI TRUNG THU T, et al. Trichomonas vaginalis Transports Virulent Mycoplasma hominis and Transmits the Infection to Human Cells after Metronidazole Treatment: A Potential Role in Bacterial Invasion of Fetal Membranes and Amniotic Fluid. Journal of pregnancy, 2018; 2018:5037181.

24. WARR AJ, et al. Sexually transmitted infections during pregnancy and subsequent risk of stillbirth and infant mortality in Kenya: a prospective study. Sexually transmitted infections, 2019; 95(1): 60-66.

25. WYNN A, et al. Prevalence and treatment outcomes of routine Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis testing during antenatal care, Gaborone, Botswana. Sexually Transmitted Infections, 2018; 94(3): 230-235.

26. WINN A, et al. Using partner notification to address curable sexually transmitted infections in a high HIV prevalence context: a qualitative study about partner notification in Botswana. BMC public health, 2019; 19(1): 606.

27. YEGANEH N, et al. Diagnosis and treatment of sexually transmitted infections in male partners of pregnant women in Brazil. International journal of STD & AIDS, 2021; 32(13): 1242-1249.