Influência da microbiota intestinal e vitamina D sobre a depressão
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Resumo
Objetivo: Analisar os principais artigos científicos da literatura médica sobre a influência da microbiota intestinal e vitamina D sobre a depressão. Métodos: Revisão integrativa da literatura por meio de buscas, nos últimos 5 anos (2019 – 2024), realizadas nas bases de dados: Scielo, PubMed, Literatura Latino-Americana e do Caribe (LILACS) e MEDLINE indexadas na Biblioteca Virtual em Saúde (BVS). Foram utilizados os seguintes operadores booleanos: “microbiota intestinal” AND “depressão”, “vitamina D” AND “depressão” e “microbiota intestinal” AND “vitamina D”. Resultados: A amostra final foi de 26 artigos, todos encontrados na plataforma PubMed; 13 artigos abordaram sobre microbiota intestinal e depressão, 8 artigos sobre microbiota intestinal e vitamina D e 5 artigos sobre vitamina D e depressão. Considerações finais: As pesquisas analisadas destacaram a complexa relação entre microbiota intestinal e vitamina D na depressão. A compreensão dos mecanismos existentes nessa relação oferece novas estratégias para o tratamento desse transtorno debilitante além dos sintomas emocionais.
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