Manipulação vertebral na lombalgia: avaliando os efeitos na intensidade da dor e nos marcadores imunológicos
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Resumo
Objetivo: Analisar os efeitos das manipulações vertebrais (MV) em adultos com dor lombar, avaliando a dor e os marcadores imunológicos. Métodos: Estudo de revisão sistemática (PROSPERO CRD42024577322), seguiu a declaração PRISMA (2020), estratégia PICO, a partir da pergunta norteadora: “Quais os efeitos das manipulações vertebrais em adultos com dor lombar na redução da intensidade da dor e na modulação dos marcadores imunológicos?”. Foi realizada uma busca nas bases Scielo, PubMed, BVS e PEDro, seguindo critérios de inclusão e exclusão predefinidos. Dos 48 artigos encontrados, apenas 04 foram selecionados para compor a revisão. Resultados: Os estudos analisados eram ensaios clínicos, com tratamento manual osteopático ou manipulação espinhal de alta velocidade e baixa amplitude, em protocolos distintos e com grupos controle, utilizaram a escala EVA para mensuração da dor. Os marcadores imunológicos analisados foram citocinas, quimiocinas, NPY, E-selectina, vitamina D e proteína C reativa. Considerações finais: A MV mostra eficácia na redução da dor em lombalgia aguda e crônica e na modulação de biomarcadores como PCR, IL-6, IL-10 e TNF-α. Os resultados sugerem que a MV é uma abordagem promissora e menos invasiva. Mais estudos são necessários para identificar quais biomarcadores mais eficazes para monitorar a evolução clínica e guiar tratamentos personalizados.
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