Overview of Pediatric Multisystemic Inflammatory Syndrome associated with Covid-19 (SIM-P) in children from the Amazon region

Abstract

Objective: To describe laboratory findings and clinical-epidemiological characteristics in children and adolescents with Pediatric Multisystemic Inflammatory Syndrome (SIM-P) associated with COVID-19 treated at a hospital in the Amazon region. Methods: This is a cross-sectional, quantitative, retrospective study, with data from 28 patients, of both sexes, attended between April and August 2020, collected through the analysis of medical records, using an adapted data collection form, considering aspects clinical, epidemiological and laboratory tests. Descriptive and analytical statistics were performed using the BioEstat® 5.320 software. After, approval by the Research Ethics Committee. Results: The sample had a mean age of 4.9 years ± 5 years, with no predominance between genders. The main signs and symptoms found were dyspnea, nausea / vomiting, abdominal pain, cough, runny nose, hand and foot swelling, and diarrhea. Among the laboratory alterations, there was an increase in troponin (100%), D-dimer, ESR (96%), hypertriglyceridemia (95%), a decrease in hemoglobin (96%), a decrease in HDL (81%), an increase in TGP (76.9%) and ferritin (76.9%). Conclusion: It is concluded that there is no predominance between genders, with a wide age range, with the most frequent clinical manifestations being respiratory and gastrointestinal. The main laboratory findings reflect high inflammatory activity and the systemic character of the disease.